张乐

生育健康流行病学

1. 妇女孕期稀土元素暴露与妊娠期高血压疾病风险的关系及机制研究，国自然面上课题（82173527），2022-01至2025-12，骨干，在研

2.胚胎植入前遗传学检测(PGT)大数据挖掘，2021-06至2025-05，在研，主持

3.郝家河流域农产品和路尘暴露风险源研究项目（子课题），2020-09至2020-12，已结题，主持

4. 国家科学技术部，重点研发计划应急专项，2020YFC0846300，新冠肺炎流行对孕妇不良妊娠结局的影响，2020-04至2020-12，已结题，骨干

5. 国家自然科学基金委员会，面上项目，41771527，华北典型地区育龄妇女多环芳烃的体外及体内暴露水平研究，2018-01至2021-12，在研，参加

6.    国家自然科学基金委员会，面上项目，31371523，多环芳烃致胎儿神经管缺陷作用及氧化应激机制研究，2014-01至2017-12，已结题，参加

7.    国家科学技术部，支撑计划，2013BAI12B00，孕前出生缺陷一级预防预警关键技术及应用研究，2013-01至2015-12，已结题，参加

1. Yushan Du, Shuangbo Xia, Jinjuan Zhang, Le Zhang*, Jufen Liu*. Plasma folate deficiency increases the risk for abnormal blood pressure in Chinese women of childbearing age. Nutrition Research, 2021, https://doi.org/10.1016/j.nutres.2021.12.003.

2. Song Q, Wei J, Wang J, Zhang L*, Liu X*, Zhang Y, Li N, Li Z. Rate of Correct Use of Folic Acid Supplementation Among Pregnant Women - Beijing Municipality, China, 2017-2019. China CDC Wkly. 2021 Sep 10;3(37):783-787.

3. Jia X, Zhang L#, Zhao J, Ren M, Li Z, Wang J, Wang S, Liu Y, An H, Li Y, Yan L, Li Z*, Liu X*, Pan B*, Ye R. Associations between endocrine-disrupting heavy metals in maternal hair and gestational diabetes mellitus: A nested case-control study in China. Environ Int. 2021 Dec;157:106770. doi: 10.1016/j.envint.2021.106770. Epub 2021 Jul 24. PMID: 34314978.

4. Xiaoqian Jia, Mengyuan Ren, Yali Zhang, Rongwei Ye, Le Zhang *, Zhiwen Li*. Association between tea drinking and plasma folate concentration among women aged 18-30 years in China. Public Health Nutrition: 4929-4936.

5. Zhang L, Zhang Y#, Li Z*, Ren A, Liu J, Ye R*. Maternal periconceptional body mass index and risk for neural tube defects: results from a large cohort study in China. J Matern Fetal Neonatal Med. 2021 Jan;34(2):274-280.

6.  Yongxiu Hao, Yiming Pang, Huina Yan, Yali Zhang, Jufen Liu, Lei Jin, Lailai Yan, Da Chen, Ligang Hu, Qian Liu, Yanan Qin, Bin Wang, Zhiwen Li, Rongwei Ye *, Le Zhang *, Aiguo Ren, Association of maternal serum copper during early pregnancy with the risk of spontaneous preterm birth: a nested case-control study in China, Environ Int, 2019,122:237-243.

7. 闫会娜,王战,王佳媚,刘晓红,张乐*,等.北京高知地区孕妇孕期咖啡因暴露情况[J].中国健康教育,2017,33(11):1005-1007,1015.

8. 孟凡文, 陈森, 刘亚山, 李楠, 杨娜, 刘莹娟, 张乐*, 叶荣伟*. 河北省5县区妊娠期高血压疾病的发病情况及危险因素分析[J]. 中国生育健康杂志, 2015, 26(2): 112-115.

9. 张乐, 孙美平, 高卫线, 洪世欣, 张亚黎*. 县、乡级超声医生开展胎儿期复杂先天性心脏病超声筛查的可行性研究[J]. 北京大学学报（医学版）, 2014, 46(3): 373-378.

10. Le Zhang, Aiguo Ren*, Zhiwen Li, Ling Hao, Yihua Tian, Zhu Li. Folate concentrations and folic acid supplementation among women in their first trimester of pregnancy in a rural area with a high prevalence of neural tube defects in Shanxi, China. Birth Defects Res A, 2006, 76(6): 461-466.