The current research mainly focused on the adverse effect of occupational and environmental factors. The majority of the work is devoted to identifying the health impact of nanoparticles and involving nanotoxicology and occupational ergonomics.
1. National key project topic, In vivo precise detection and metabolism of in situ assembly of peptide nanosystems, 2023.5-2028.04. PI.
2. Capital's Funds for Health Improvement and Research (CFH 2022-2G-30111), Investigation and Intervention Study on the Exposure of third-hand smoke in Beijing Children's Families, 2022/01-2024/12, CO-PI
3. National Natural Science Foundation of China (31971313), Effects of titanium dioxide nanoparticles on the occurrence and development of colorectal carcinoma and its mechanism,2020.1-2023.12. PI.
4. Beijing Natural Science Foundation (7172116), The impact of titanium dioxide nanoparticles on inflammatory bowel disease: role of oxidative stress and antioxidant therapy, 2017.1-2019.12. PI
5. National Natural Science Foundation of China (31400863), The effect and mechanism of TiO2 nanoparticles on intestinal mucosal barrier dysfunction, 2015.1-2017.12. PI
6. Beijing Natural Science Foundation (7132117), Effect of titanium dioxide nanoparticles on glucose absorption and metabolism, 2013.1-2015.6. PI
1. Shumin Duan, Hongbo Wang, Yanjun Gao, Xiang Wang, Lizhi Lyu, Yun Wang*. Oral intake of titanium dioxide nanoparticles affect the course and prognosis of ulcerative colitis in mice: involvement of the ROS-TXNIP-NLRP3 inflammasome pathway. Particle and Fibre Toxicology, 2023, 20, 24. (IF2022=10.0)
2. Lizhi Lyu, Yu Xu, Hongbo Wang, Xin Guo, Yanjun Gao, Shumin Duan, Furong Deng, Xinbiao Guo, Yun Wang*. Changes in heart rate variability of healthy subjects shortly exposed to printing shop particles and the effect of air purifier intervention. Environmental Pollution, 2022, 315, 120418. (IF2022=8.9)
3. Lizhi Lyu, Yuan Li, Xiaxian Ou, Wanqian Guo, Yi Zhang, Shumin Duan, Yanjun Gao, Yu Xu, Tianzhuo Yang, Yun Wang*. Health effects of occupational exposure to printer emissions on workers in China: Cardiopulmonary function change. NanoImpact, 2021, 21: 100289. (IF2021=6.038)
4. Yanjun Gao, Tingyu Li, Shumin Duan, Lizhi Lv, Yuan Li, Lin Xu, Yun Wang*. Impact of titanium dioxide nanoparticles on intestinal community in the 2,4,6-Trinitrobenzenesulfonic acid (TNBS)-induced acute colitis mice and the intervention effect of vitamin E. Nanoscale, 2021, 13: 1842-1862.(IF2021=8.307)
5. Yongliang Zhang, Shumin Duan, Ying Liu, Yun Wang*. The combined effect of food additive titanium dioxide and lipopolysaccharide on mouse intestinal barrier function after chronic exposure of titanium dioxide-contained feedstuffs. Particle and Fibre Toxicology, 2021, 18, 8.(IF2021=9.112)
6. Yanjun Gao, Yixuan Ye, Jing Wang, Hao Zhang, Yao Wu, Yihui Wang, Lailai Yan, Yongliang Zhang, Shumin Duan, Lizhi Lv, Yun Wang*. Effects of titanium dioxide nanoparticles on nutrient absorption and metabolism in rats: distinguishing the susceptibility of amino acids, metal elements, and glucose. Nanotoxicology, 2020, 14(10): 1301-1323. (IF2020=5.913)
7. Sandra V. Pirela#, Kunal Bhattacharya#, Yun Wang#(co-first), Yipei Zhang, Guanghe Wang, Costas A. Christophi, John Godleski, Treye Thomas, Yong Qian, Marlene S. Orandle, Jennifer D. Sisler, Dhimiter Bello, Vincent Castranova, Philip Demokritou*. A 21-day sub-acute, whole-body inhalation exposure to printer-emitted engineered nanoparticles in rats: Exploring pulmonary and systemic effects. NanoImpact, 2019, 15: 100176. (IF2019=5.478)
8. Zhangjian Chen, Yun Wang*, Lin Zhuo, Shi Chen, Lin Zhao, Tian Chen, Yang Li, Wenxiao Zhang, Xin Gao, Ping Li, Haifang Wang, Guang Jia*. Interaction of titanium dioxide nanoparticles with glucose on young rats after oral administration. Nanomedicine: Nanotechnology, Biology and Medicine, 2015, 11(7): 1633-1642. (IF2015=5.671)
9. Yun Wang, Zhangjian Chen, Te Ba, Ji Pu, Tian Chen, Yanshuang Song, Yongen Gu, Qin Qian, Yingying Xu, Kun Xiang, Haifang Wang, Guang Jia*. Susceptibility of young and adult rats to the oral toxicity of titanium dioxide nanoparticles. Small, 2013, 9(9–10): 1742–1752. (IF2013=7.514;Highlighted by Materials Views China from Wiley;健康报2013-9-13周五第2版报道)
10. Yun Wang#, Bing Wang#, Motao Zhu, Ming Li, Huajian Wang, Meng Wang, Hong Ouyang, Zhifang Chai, Weiyue Feng*, Yuliang Zhao. Microglial activation, recruitment and phagocytosis as linked phenomena in ferric oxide nanoparticles exposure. Toxicology Letters, 2011, 205(1): 26-37. (IF2011=3.230)